Fehér por GS-441524 CAS 1191237-69-0
- yanxi
- Kína
- 3-10 nap
- 100000 kg/év
Bevezetés:
A GS-441 a nukleozid-trifoszfát kompetitív inhibitora. Gátolja számos különböző típusú RNS replikációját, mint például a súlyos akut légúti szindróma (SARS), a közel-keleti légúti szindróma, az ebola, a Lassa-láz, a Junin és a légúti syncytium stb., és a sejtek széles körében alacsony citotoxicitása vonalak.
Funkció:
A Gs-441-et a sejtkináz nukleozid-monofoszfáttá (NMP) foszforilezi, majd aktív trifoszfát metabolittá (NTP szerkezeti analóg) alakítja át. Az RNS-szintézisben az aktív NTP szerkezeti analógok természetes nukleozid-trifoszfát-konkurensként működnek, és versengenek a természetes nukleozidokkal (ATP, TTP, CTP, GTP), hogy részt vegyenek az RNS-transzkripcióban. Amikor a gs-441-et beépítjük a transzkriptumokba, a transzkripció korán leáll, így gátolja az RNS-transzkripciós folyamatot.
White Powder GS-441524 CAS 1191237-69-0
Product Description
Name:(2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS No.:1191237-69-0
Place of Origin: China (Mainland)
Grade Standard: Pharmaceutical Grade
Brand Name: JINLAN PHARM
We recommend T/T or Escrow , D/P,D/A, Western Union or PayPal are also acceptable!
Delivery:
Express way as the following is:
(Shipping : TNT, Fedex, DHL,USP,EMS and so on)
Packaging:
Drum & plastic bags, Aluminum foiled bag, Zip lock bags
Our Company:
Our company advantage:
1.Small order is acceptable
2.Can provide sample for you
3.Have self-export rights
Our Advantages
Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service:
1)International Authorized Third-Party Test For The Products You Demand.
2)60 Days Warranty of quality of goods.
FAQ
Q1. How does your factory control quality?
A:All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.
Q2. What's your main markets?
A:North America, Europe, Asia, etc.
Q3. What is your delivery term and delivery period?
A:We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. The sample within 3 days, and bulk order within 5 days.
Q4. What is your package?
A:Powder: PE bag, glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.
Q5. What is the payment term?
A:Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.
Q6. Will you supply samples for test the quality?
A:We'd like to offer our customers the free samples for the quality evaluation for most products, but the shipping cost is borne by customers.
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